Dr. Melianthe Nicolai

  • Netherlands Cancer Institute

Professional Experience

2003-2011                  Medical School (MD), Leiden University, the Netherlands

Nov 27th, 2014          PhD, Leiden University, the Netherlands, Thesis: Omissions in care for sexual health in Cardiology and Gastroenterology

Nov 2020- present: Urologist/andrologist Diakonessen hospital Utrecht, the Netherlands

Jan 2021- present:  Urologist Antoni van Leeuwenhoek hospital/Netherlands Cancer Institute. Outpatient clinic: ‘Sex after Cancer’ and post doctoral researcher in the field of sexual quality of life after cancer and disease.

Expertise and Research Interests

Expertise: Urology, sexology, integrative and preventive medicine/lifestyle medicine, endourology, men’s sexual health

Research interests:

– Penile rehabilitation after nerve sparing Radical prostatectomy,

– Quality of life after penile cancer.

– Quality of sexual healthcare in radiotherapy, farmacology and urology

Selected Publications

                                                                          

  1. Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury. Dear JW, Simpson KJ, Nicolai MP, Catterson JH, Street J, Huizinga T, Craig DG, Dhaliwal K, Webb S, Bateman DN, Webb DJ. J Immunol. 2011 Sep 15;187(6):3347-52.
  2. Sexual abuse history in GI illness, how do gastroenterologists deal with it? Nicolai MP, Fidder HH, Beck JJ, Bekker MD, Putter H, Pelger RC, van Driel MF, Elzevier HW. J Sex Med. 2012 May;9(5):1277-84.
  1. Pelvic floor complaints in gastroenterology practice: results of a survey in the Netherlands. Nicolai MP, Fidder HH, Bekker MD, Putter H, Pelger RC, Elzevier HW. Frontline Gastroenterol. 2012 Jul;3(3):166-171.
  1. Discussing sexual function in the cardiology practice. Nicolai MP, Both S, Liem SS, Pelger RC, Putter H, Schalij MJ, Elzevier HW. Clin Res Cardiol. 2013 May;102(5):329-36.
  1. Urological Complaints and Sexual Abuse: A Case Control Study Identifying Multiple Urological Complaints in Relation to Sexual Abuse History. Beck JH, Nicolai MP, Putter H, Pelger R, Elzevier HW. Advances in Sexual Medicine, 2013, 3, 39-46
  1. What do cardiologists know about the effects of cardiovascular agents on sexual function? A survey among Dutch cardiologists. Part I. Nicolai MP, Liem SS, Both S, Pelger RC, Putter H, Schalij MJ, Elzevier HW. Neth Heart J. 2013 Dec;21(12):540-4.
  1. A review of the positive and negative effects of cardiovascular drugs on sexual function: a proposed table for use in clinical practice. Nicolai MP, Liem SS, Both S, Pelger RC, Putter H, Schalij MJ, Elzevier HW. Neth Heart J. 2014  Jan;22(1):11-9.
  1. Erectile dysfunction in the cardiology practice-a patients’ perspective. Nicolai MP, van Bavel J, Somsen GA, de Grooth GJ, Tulevski II, Lorsheyd A, Putter H, Schalij MJ, Pelger RC, Elzevier HW. Am Heart J. 2014 Feb;167(2):178-85.
  1. The impact of sexual abuse in patients undergoing colonoscopy. Nicolai MP, Keller JJ, de Vries L, van der Meulen-de Jong AE, Nicolai JJ, Hardwick JC, Putter H, Pelger RC, Elzevier HW. PLoS One. 2014 Jan 15;9(1)
  1. Do residents in cardiology need more training to make them talk about sex? Nicolai MP, Elzevier HW. Neth Heart J. 2014 Mar;22(3):122-3.
  1. Addressing changed sexual functioning in cancer patients: A cross-sectional survey among Dutch oncology nurses. Krouwel EM,Nicolai MP, van Steijn-van Tol AQ, Putter H, Osanto S, Pelger RC, Elzevier HW. Eur J Oncol Nurs. 2015 Jun 4. pii: S1462-3889(15)00079-4.
  2. Management of sexual side effects in the surgical oncology practice: A nationwide survey of Dutch surgical oncologists. Krouwel EM, Hagen JH, Nicolai MP, Vahrmeijer AL, Putter H, Pelger RC, Elzevier HW. Eur J Surg Oncol. 2015 Sep;41(9):1179-87.
  3. Discussing Sexual Dysfunction with Chronic Kidney Disease Patients: Practice Patterns in the Office of the Nephrologist. van Ek GF, Krouwel EM, Nicolai MP, Bouwsma H, Ringers J, Putter H, Pelger RC, Elzevier HW. J Sex Med. 2015 Dec 3.
  4. Sexual Concerns after (Pelvic) Radiotherapy: Is There Any Role for the Radiation Oncologist? Krouwel EM, Nicolai MP, van der Wielen GJ, Putter H, Krol AD, Pelger RC, Incrocci L, Elzevier HW. J Sex Med. 2015 Sep;12(9):1927-39.
  5. Wandering Wire…Where? -A Heartrending Report. Douma MR, Burg MD, Nicolai MP, Wiersema A. Emerg Med. 2015 Oct 22.
  1. Discussing reproductive health in spinal care, part II: fertility issues. Korse NS, Nicolai MP, Both S, Vleggeert-Lankamp CL, Elzevier HW. Eur Spine J. 2016 Sep;25(9):2945-51.
  1. Dealing with patients facing a history of sexual abuse: A cross-sectional survey among Dutch general practitioners. Birkhoff EM, Krouwel EM, Nicolai MP, de Boer BJ, Beck JJ, Putter H, Pelger RC, Elzevier HW. Eur J Gen Pract. 2016 Jun; 22(2):126-33. doi: 10.3109/13814788.2015.1122752.
  2. Does total hip replacement affect sexual quality of life? Harmsen RT, Haanstra TM, Sierevelt IN, Jansma EP, Nolte PA, Nicolai MP, Wall PD, Van Royen BJ. BMC Musculoskelet Disord. 2016 May 4;17:198. doi: 10.1186/s12891-016-1048-1.
  1. Discussing sexual health in spinal care. Korse NS, Nicolai MP, Both S, Vleggeert-Lankamp CL, Elzevier HW. Eur Spine J. 2016 Mar;25(3):766-73. doi: 10.1007/s00586-015-3991-1.
  1. Does total hip replacement affect sexual quality of life? Harmsen RT, Haanstra TM, Sierevelt IN, Jansma EP, Nolte PA, Nicolai MP, Wall PD, Van Royen BJ. BMC Musculoskelet Disord. 2016 May 4;17:198. doi: 10.1186/s12891-016-1048-1.
  1. Indwelling Urinary Catheter-Related Problems After Laparoscopic Radical Prostatectomy. Reuvers S, Zonneveld W, Meiland-van Bakel M, Putter H, Nicolai M, Pelger R, Elzevier H. J Wound Ostomy Continence Nurs. 2016 Jul-Aug;43(4):420-4.
  1. Fertility preservation counselling in Dutch Oncology Practice: Are nurses ready to assist physicians? Krouwel EM, Nicolai MPJ, van Steijn-van Tol AQMJ, Putter H, Osanto S, Pelger RCM, Elzevier HW. Eur J Cancer Care (Engl). 2017 Nov; 26(6).
  2. In response to letter to the editor: Time to integrate sexual function in the health-related quality of life of patients with left ventricular assist devices: The problem is the implementation of sexual healthcare in cardiology. Nicolai MP, Elzevier HW. Heart Lung. 2017 Mar – Apr;46(2):133-134.
  3. What is the role of nephrologists and nurses of the dialysis department in providing fertility care to CKD patients? A questionnaire study among care providers. van Ek GF, Krouwel EM, Nicolai MPJ, Den Oudsten BL, Den Ouden MEM, Dieben SWM, Putter H, Pelger RCM, Elzevier HW. Int Urol Nephrol. 2017 Jul;49(7):1273-1285. doi: 10.1007/s11255-017-1577-z.
  1. Patient sexual function and hip replacement surgery: A survey of surgeon attitudes. Harmsen RTE, Nicolai MPJ, Den Oudsten BL, Putter H, Haanstra TM, Nolte PA, Van Royen BJ, Elzevier H. Int Orthop. 2017 Dec;41(12):2433-2445.
  1. Sexual care for patients receiving dialysis: A cross-sectional study identifying the role of nurses working in the dialysis department. van Ek GF, Gawi A, Nicolai MPJ, Krouwel EM, Den Oudsten BL, Den Ouden MEM, Schaapherder AF, Putter H, Pelger RCM, Elzevier HW. J Adv Nurs. 2018 Jan;74(1):128-136.
  2. The Discussion of Sexual Dysfunction Before and After Kidney Transplantation From the Perspective of the Renal Transplant Surgeon. van Ek GF, Krouwel EM, van der Veen E, Nicolai MPJ, Ringers J, Den Oudsten BL, Putter H, Pelger RCM, Elzevier HW. Prog Transplant. 2017 Dec;27(4):354-359.
  3. Unravelling current sexual care in chronic kidney disease: perspective of social workers. van Ek GF, Keurhorst D, Krouwel EM, Nicolai MPJ, Den Ouden MEM, Elzevier HW, Putter H, Pelger RCM, Den Oudsten BL. J Ren Care. 2018 Mar;44(1):30-37.
  1. Adverse drug reactions on sexual functioning: a systematic overview. Gordijn R, Teichert M, Nicolai MPJ, Elzevier HW, Guchelaar HJ. Drug Discov Today. 2019 Mar;24(3):890-897. doi: 10.1016/j.drudis.2019.01.012. Epub 2019 Jan 25. Review.
  2. Discussing Sexual Health in the Medical Oncologist’s Practice: Exploring Current Practice and Challenges. Krouwel EM, Albers LF, Nicolai MPJ, Putter H, Osanto S, Pelger RCM, Elzevier HW. J Cancer Educ. 2019 Jun 17. doi: 10.1007/s13187-019-01559-6.
  3. Consulting “Dr Google” for sexual dysfunction: a contemporary worldwide trend analysis. Russo GI, di Mauro M, Cocci A, Cacciamani G, Cimino S, Serefoglu EC, Albersen M, Capogrosso P, Fode M, Verze P; EAU-YAU Men’s Health Working Group. Int J Impot Res. 2019 Oct 7. doi: 10.1038/s41443-019-0203-2. PMID: 31591474
  4. Undiagnosed prediabetes status is associated with a reduced effectiveness of phosphodiesterase type 5 inhibitors in men with erectile dysfunction. Di Mauro M, Nicolai M, Russo GI; EAU-YAU Men’s health working party. Int J Impot Res. 2019 Oct 28. doi: 10.1038/s41443-019-0205-0.
  1. Vascular Surgeons’ Views on Ejaculation Disorders After Abdominal Aortic Surgery: Results of a Dutch Survey. Jan van Schaik, Joost R van der Vorst , Jaap F Hamming , Henk W Elzevier , Melianthe P J Nicolai. Ann Vasc Surg. 2020 Apr 1;S0890-5096(20)30221-1. doi: 10.1016/j.avsg.2020.02.021.
  2. Book: Peyronie’s Disease: Pathophysiology and Treatment. Chapter 5: Traction and Vacuüm devices; Nicolai and J. Beck, Edited by Giorgio Ivan Russo and Andrea Cocci,      ISBN: 978-0-12-819468-3, Publisher: Elsevier, VOLUME: 1, PUB DATE: May 2020
  3. Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study). Krouwel EM, Jansen TG, Nicolai MPJ, Dieben SWM, Luelmo SAC, Putter H, Pelger RCM, Elzevier HW. Cancers (Basel). 2021 Feb 1;13(3):553. doi: 10.3390/cancers13030553. PMID: 33535586; PMCID: PMC7867120.
  4. Penile Rehabilitation and Treatment Options for Erectile Dysfunction Following Radical Prostatectomy and Radiotherapy: A Systematic Review. Nicolai M, Urkmez A, Sarikaya S, Fode M, Falcone M, Albersen M, Gul M, Hatzichristodoulou G, Capogrosso P, Russo GI. Front Surg. 2021 Mar 2;8:636974. doi: 10.3389/fsurg.2021.636974. PMID: 33738297; PMCID: PMC7961076.
  5. Learning From Consultations Conducted by Community Pharmacists in Northern Ireland for Nonprescription Sildenafil: A Qualitative Study Using the Theoretical Domains Framework. Gordijn R, Teichert M, Nicolai MPJ, Elzevier HW, Guchelaar HJ, Hughes CM. Sex Med. 2021 Oct 7;9(6):100440. doi: 10.1016/j.esxm.2021.100440. Online ahead of print. PMID: 34628114
  6. An Educational Need Regarding Treatment-Related Infertility and Fertility Preservation: a National Survey Among Members of the Dutch Society for Medical Oncologists. Krouwel EM, Birkhoff EML, Nicolai MPJ, Osanto S, Putter H, Pelger RCM, Elzevier HW.J Cancer Educ. 2021 Oct 8. doi: 10.1007/s13187-021-02084-1. Online ahead of print.PMID: 34623602
  1. An estimation of patients at potential risk for drug-induced sexual dysfunction using pharmacy dispensing data. Gordijn R, Nicolai MPJ, Elzevier HW, Guchelaar HJ, Teichert M.Fam Pract. 2021 Jun 17;38(3):292-298. doi: 10.1093/fampra/cmaa116