Prof. Silvana Andric

  • Faculty of Sciences at University of Novi Sad

Professional Experience

PhD in male reproductive endocrinology (University of Novi Sad, Faculty of Sciences), post-doctoral training in cell signaling related to reproductive endocrinology (National Institutes of Health, NICH, ERRB). 30 years of experience in research related to male reproductive biology (https://www.researchgate.net/profile/Silvana-Andric) and 20 years of experience in teaching different courses related to reproductive biology and cell signaling.

Expertise and Research Interests

Areas of expertise: reproductive biology, cell signaling, mitoch. dynamic regulation.

Current research activities are oriented to investigation of the mechanisms of male (in/sub)fertility. (1) The multiscale concept and the integrative reproductive physiology network approach to decode role of mitochondrial dynamics in lifestyle-directed (in/sub)fertility. (2) The “horizontal” communication between functionally different, but yet connected cells (spermatozoa and PBMC). (3) The role of mitochondrial dynamics in lifestyle-directed (in/sub)fertility and the mitochondrial dynamics maps in human spermatozoa and PMBCs from PTSD individuals.

http://wwwold.dbe.pmf.uns.ac.rs/en/nauka-eng/lares; https://mito-rebels.pmf.uns.ac.rs/mito-rebels-engl/

Further areas of expertise: molecular and cellular physiology, steroidogenesis, stress.

Selected Publications

(1) Starovlah IM, Radovic Pletikosic SM, Kostic TS & Andric SA (2021): Mitochondrial dynamics markers and related signaling molecules are important regulators of spermatozoa number and functionality. Int J Mol Sci 22(11):5693.

(2) Radovic Pletikosic SM, Starovlah IM, Miljkovic D, Bajic DM, Capo I, Nef S, Kostic TS & Andric SA (2021): Deficiency in insulin-like growth factors signaling in mouse Leydig cells increase conversion of testosterone to estradiol due to feminization. Acta Physiol (Oxf) 2020 Sep 25:e13563. doi: 10.1111/apha.13563.

*Editorial about the article (The Insulin/Insulin-like Growth Factor signaling connects metabolism with sexual differentiation) is available on https://onlinelibrary.wiley.com/doi/10.1111/apha.13576

(3) Starovlah IM, Radovic SM, Kostic TS & Andric SA (2020): Reduced spermatozoa functionality during stress is the consequence of adrenergic-mediated disturbance of mitochondrial dynamics markers. Sci Rep 10 (1):16813.

(4) Radovic SM, Starovlah IM, Capo I, Miljkovic D, Nef S, Kostic TS & Andric SA (2019): Insulin/IGF1 signalling regulates the mitochondrial biogenesis markers in steroidogenic cells of prepubertal testis, but not ovary. Biol Reprod 100(1):253-267.

(5) Gak IA*, Radovic SM*, Dukic AR, Janjic MM, Stojkov-Mimic NJ, Kostic TS & Andric SA (2015): Stress stimulates mitochondrial biogenesis to preserve steroidogenesis in Leydig cells of adult rats.  BBA Mol Cell Res 1853: 2217-2257.